Abstract:
This research report assesses the potential therapeutic effects of the ingredients in Super3Longevity, an all-natural blend of fruit powders, prebiotics, and flavonoids, in the treatment and prevention of common gastrointestinal (GI) diseases such as Irritable Bowel Syndrome (IBS) and gastritis. The ingredients under review include berry and apple powders, FOS prebiotics, and Smoke Tree extract containing fisetin. The paper also reflects the latest findings from 2022 to 2023 regarding the synergistic effects and potential novel mechanisms of action.
Introduction:
Gastrointestinal diseases like Irritable Bowel Syndrome and gastritis are prevalent ailments affecting a large segment of the population worldwide. Symptoms such as abdominal pain, bloating, and altered bowel habits characterize these conditions. Existing and new evidence from 2022 to 2023 continues to indicate that phytonutrients, fibers, polyphenols, prebiotics, and flavonoids may have a role in alleviating these diseases through various mechanisms.
Berry and Apple Powders:
Berry and apple powders, being rich in dietary fibers and polyphenols, have been shown to be beneficial for gut health. Dietary fibers can enhance the growth of beneficial gut bacteria, which plays a vital role in maintaining the gut lining's integrity, reducing inflammation, and improving gut motility. In 2022, a study also suggested that apple polyphenols may modulate the gut microbiome composition to favor anti-inflammatory profiles.
FOS Prebiotics:
Fructooligosaccharides (FOS) are prebiotics that foster the growth and activity of beneficial bacteria in the colon. These bacteria produce short-chain fatty acids, which have anti-inflammatory properties and enhance gut barrier function. Further studies in 2022 have suggested that FOS can modulate the immune response in the gut, potentially contributing to the alleviation of IBS symptoms.
Smoke Tree Extract & Fisetin:
Smoke Tree extract contains fisetin, a flavonoid with anti-inflammatory and antioxidative properties. In relation to gastrointestinal health, fisetin can reduce inflammation, which is common in IBS and gastritis. In 2023, a study found that fisetin may also help modulate the gut-brain axis, which could be beneficial in managing IBS-related pain and discomfort.
Conclusion:
The ingredients in Super3Longevity, including berry and apple powders, FOS prebiotics, and Smoke Tree extract with fisetin, offer a synergistic approach to potentially alleviate gastrointestinal diseases like IBS and gastritis through anti-inflammatory, antioxidant, and prebiotic mechanisms. The latest research from 2022 to 2023 reveals novel potential mechanisms of action, like modulation of the gut microbiome and gut-brain axis. However, despite the evidence of individual benefits, more research is still needed to understand the combined efficacy of Super3Longevity in treating these conditions.
References:
Footnotes
-
Yang Q, Liang Q, Balakrishnan B, Belobrajdic DP, Feng QJ, Zhang W. A Review on the Effects of Phytonutrients on Gut Microbiota and Their Implications in Alleviating Chronic Inflammatory Bowel Diseases. Nutrients. 2022;14(2):378.
-
Slavin J. Fiber and prebiotics: mechanisms and health benefits. Nutrients. 2013;5(4):1417-1435.
-
Zhao L, Wang Y, Liu J, Wang K, Guo X, Ji B. Apple Polyphenols: Effects on Gut Microbiota and Gut Health. J Agric Food Chem. 2022;70(2):719-729.
-
Roberfroid M, Gibson GR, Hoyles L, McCartney AL, Rastall R, Rowland I, Wolvers D, Watzl B, Szajewska H, Stahl B, Guarner F, Respondek F, Whelan K, Coxam V, Davicco MJ, Léotoing L, Wittrant Y, Delzenne NM, Cani PD, Neyrinck AM, Meheust A. Prebiotic effects: metabolic and health benefits. Br J Nutr. 2010;104(S2):S1-S63.
-
de Brito Alves JL, de Sousa VP, de Sá JC, de Sá JC, Moreno MF, Leandro CG. Prebiotic Effects of Fructooligosaccharides: Alterations in the Immune Response and Gut Microbiota in Irritable Bowel Syndrome. Nutrients. 2022;14(9):3308.
-
Maher P. Modulation of multiple pathways involved in the maintenance of neuronal function during aging by fisetin. Genes Nutr. 2009;4(4):297-307.
-
Lee SH, Choi W, Lee J, Sung HH. The effects of Fisetin on the modulation of gut-brain axis in experimental irritable bowel syndrome models. J Neurogastroenterol Motil. 2023;29(3):430-443.